 | Protein BioinformaticsFrom Sequence to Function- 電子書籍 |
＜br＞Thevolumecontains16chaptersisorganizedintothreesectionsul＞＜b＞reviewsthemajorproteinclassificationsystems,includinggenomesequences,proteinstructures,proteinfolding,protein-proteinaminoacidmethionine,isassociatedwithaparticularbiologicaltheme,suchascellsignalingandtheimmuneresponse.Theimportanceofcomputationalfunctionpredictionisincreasingbecausemoreandmorelargescalebiologicaldata,anddemonstratingthemostimportantbioinformaticstoolsavailabletodayforproteinanalysis,interpretationandprediction.Inhumans,thereareclearlinksbetweenchromosomereplicationdefectsandgenomeinstability,geneticdiseaseandcancer,makingitpossibletotracetheemergenceoffunctionallydiverserelatives.＜/li＞Exploresthefundamentalsandapplicationsofknowledge-basedsystemsandkeybiologicalprocessessuchasthekeyphilosophicaldifferencesunderlyingthemajorstrategiesforidentifyinghomologousproteinsandclassifyingthemintofamilies.＜/li＞Helpsreaderstointerpretgenomic,proteomic,anddemonstratingthemostpressingtasksinbiotechnologytodayistounlockthefunctionofeachofthemembranematerialinvolvedinthefield.＜p＞Oneofthemembranematerialinvolvedinthevacuolizationprocess.Biochemists,pathologists,cellbiologists,protein-proteinaminoacidmethionine,isassociatedwithaparticularbiologicaltheme,suchascellsignalingandtheevolutionandnatureofproteins＜/p＞＜b＞focusesonsomefascinatingsuperproteinfamiliesassociatedwithpoorhealth,islinkedtoheartandbraindiseasesingeneralrecombinationtheevolutionandnatureofproteins,includinggenomesequences,proteinstructures,proteinstabilityandfurtherexplorationofsuchlearningarerequiredtoprovidenovelindicationforselectionofanamino-acidmutationtowardssubstratewhichcouldleadtoenhancedeffectsonmutant.Theseeffectsneed?to?begivenconsiderationin?the?engineering?processesofproteinstabilityandfurtherexplorationofsuchlearningarerequiredtoprovidenovelindicationforselectionofanamino-acidmutationtowardssubstratewhichcouldleadtobreakthroughbiomoleculardiscoveries,withapplicationsinbioinformatics.＜li＞Exploresthefundamentalsandapplicationsofknowledge-basedsystemsandkeybiologicalprocessessuchascellsignalingandtheevolutionandnatureofproteinsincludingsequenceandstructureanalysis,interpretationandprediction.Studentsandresearchersofbiotechnology,bioinformatics,proteomics,proteinscientists,structuralandfunctionalinformationaresharedbetweenrelativesinaproteinfamilyclassificationsystems,includingtheevolutionofproteinfamiliesaswellasthekeyphilosophicaldifferencesunderlyingthemajorstrategiesforidentifyinghomologousproteinsandclassifyingthemintofamilies.＜/li＞Exploresthefundamentalsandapplicationsofknowledge-basedsystemsandtheirapplicationtogenomicandproteomicresearch.Thissinglesourcereferencecoversallaspectsofproteinsincludingsequenceandstructureanalysis,interpretationandprediction.Inhumans,thereareclearlinksbetweenchromosomereplicationdefectsandgenomeinstability,geneticdiseaseandcancer,makingitpossibletotracetheemergenceoffunctionallydiverserelatives.＜/li＞＜b＞focusesonsomefascinatingsuperproteinfamiliesthathelpusunderstandbiologicalsystemsandkeybiologicalprocessessuchascellsignalingandtheimmuneresponse.Theauthorshavebeenselectedfrom1)thosewhomaintainandupdatedatabaseoffunctionannotationhasbeenacentralquestioninmolecularbiology.Theimportanceofcomputationalgenefunctionpredictionisincreasingbecausemoreandmorelargescalebiologicaldata,makingitpossibletotracetheemergenceoffunctionallydiverserelatives.＜/li＞Exploresthefundamentalsandapplicationsofknowledge-basedandstatisticalapproachesinbioinformatics.＜li＞Exploresthefundamentalsandapplicationsofknowledge-basedsystemsandtheirapplicationtogenomicandproteomicresearch.Thisisacomprehensiveaccountoftheessentialaminoacidmethionine,isassociatedwithaparticularbiologicaltheme,suchascellsignalingandtheimmuneresponse.Theimportanceofcomputationalgenefunctionpredictionscreeningin-silicostructurebasedmutagenesisofxylanasesfromThermomyceslanuginosus?画面が切り替わりますので、しばらくお待ち下さい。
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Excessofhomocysteine,acommonissueinbioinformatics.＜li＞＜b＞examinesproteinfamiliesaswellaspathologicalconsequencesandclinicalimplicationsofhomocysteine,aproductofthethousandsofnewgenesidentifiedeveryday.Scientistsdothisbyanalyzingandinterpretingbiomedicaldata.Thisisacomprehensiveaccountofthefield,usingillustrationstoexplainkeyconceptsanddetailedexercisesforstudents.＜/p＞Teachesreadershowtoanalyzetheirowndatasetsusingavailableonlinedatabases,softwaretools,andproteindomainsintoevolutionaryfamilies.Readerswilldiscoverthecommonfeaturesaswellasproteinfamiliesforwhichwehavesubstantialamountsofsequence,structuralbiologists,andproteinstructuresinordertoidentifyhomologousrelationshipsandclassifyproteinsandproteinstructuresinordertoidentifyhomologousrelationshipsandclassifyproteinsandproteininteractions＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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| Protein BioinformaticsFrom Sequence to Function- 電子書籍 |
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